| Gene Information | |
|---|---|
| Gene Name | NCF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 526 |
| Protein Names | Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox) |
| Target Name | nadph oxidase |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000116701 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P19878 |
| Gene Card | NCF2 |
| Uniprot ID | P19878 |
| Pfam | PF00564; PF00018; PF13181 |
| In ASD | no |
| Allosteric Prediction | yes (0.383615237) |
| Ortholog in Animals | Alpaca_ NCF2 ( ortholog_one2one ) Dog_ NCF2 ( ortholog_one2one ) GuineaPig_ NCF2 ( ortholog_one2one ) Macaque_ NCF2 ( ortholog_one2one ) Mouse_ Ncf2 ( ortholog_one2one ) Pig_ NCF2 ( ortholog_one2one ) Rat_ Ncf2 ( ortholog_one2one ) Rabbit_ NCF2 ( ortholog_one2one ) |
| Ohnologs | NOXA1 |
| Paralogs | NOXA1 |
| Tissue | whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1E96 (X-ray 2.40A ) 1HH8 (X-ray 1.80A ) 1K4U (NMR - ) 1OEY (X-ray 2.00A ) 1WM5 (X-ray 1.95A ) 2DMO (NMR - ) |
| DBSNP | rs137854514 rs137854510 rs137854510 rs119103275 rs137854519 rs137854512 rs137854507 rs137854515 rs137854509 rs119103274 rs137854516 rs137854520 rs137854517 rs2274064 rs137854518 rs137854508 rs13306581 rs35937854 rs137854511 rs137854513 rs17849502 rs13306575 rs35012521 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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