| Gene Information | |
|---|---|
| Gene Name | MMP20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 483 |
| Protein Names | Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin) |
| Target Name | matrix metalloproteinase-20 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000137674 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O60882 |
| Gene Card | MMP20 |
| Uniprot ID | O60882 |
| Pfam | PF00045; PF00413; PF01471 |
| In ASD | no |
| Allosteric Prediction | no (-0.563986736) |
| Ortholog in Animals | Alpaca_ MMP20 ( ortholog_one2one ) Dog_ MMP20 ( ortholog_one2one ) GuineaPig_ MMP20 ( ortholog_one2one ) Macaque_ MMP20 ( ortholog_one2one ) Mouse_ Mmp20 ( ortholog_one2one ) Pig_ MMP20 ( ortholog_one2one ) Rat_ Mmp20 ( ortholog_one2one ) Rabbit_ MMP20 ( ortholog_one2one ) |
| Ohnologs | MMP25, MMP2, MMP11, MMP15, MMP17, MMP16 |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP27, MMP17, MMP25, MMP28, MMP13, MMP7, MMP26, HPX, MMP8, MMP3, MMP11 |
| Tissue | NA |
| Tissue Specificity | Expressed specifically in the enamel organ. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JSD (NMR - ) |
| DBSNP | rs2245803 rs17099014 rs17099008 rs1784423 rs1784424 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | HPG |
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