| Gene Information | |
|---|---|
| Gene Name | NCAN |
| Organism | Homo sapiens (Human) |
| Gene Length | 1321 |
| Protein Names | Neurocan core protein (Chondroitin sulfate proteoglycan 3) |
| Target Name | neurocan core protein |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000130287 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O14594 |
| Gene Card | NCAN |
| Uniprot ID | O14594 |
| Pfam | PF00008; PF00059; PF00084; PF07686; PF00193 |
| In ASD | no |
| Allosteric Prediction | no (-0.809468156) |
| Ortholog in Animals | Alpaca_ NCAN ( ortholog_one2one ) Dog_ NCAN ( ortholog_one2one ) Macaque_ NCAN ( ortholog_one2one ) Mouse_ Ncan ( ortholog_one2one ) Pig_ NCAN ( ortholog_one2one ) Rat_ Ncan ( ortholog_one2one ) Rabbit_ NCAN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BCAN, HAPLN1, ACAN, HAPLN3, VCAN, HAPLN2, HAPLN4 |
| Tissue | brain, cerebral.cortex, amygdala, caudate.nucleus, cerebellum, hippocampus, hypothalamus, nucleus.accumbens, putamen |
| Tissue Specificity | Brain. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2228601 rs2228603 rs1064389 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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