| Gene Information | |
|---|---|
| Gene Name | EBI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 229 |
| Protein Names | Interleukin-27 subunit beta (IL-27 subunit beta) (IL-27B) (Epstein-Barr virus-induced gene 3 protein) (EBV-induced gene 3 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105246 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q14213 |
| Gene Card | EBI3 |
| Uniprot ID | Q14213 |
| Pfam | PF00041 |
| In ASD | no |
| Allosteric Prediction | no (-0.70802073) |
| Ortholog in Animals | Alpaca_ EBI3 ( ortholog_one2one ) Dog_ EBI3 ( ortholog_one2one ) GuineaPig_ EBI3 ( ortholog_one2one ) Mouse_ Ebi3 ( ortholog_one2one ) Pig_ EBI3 ( ortholog_one2one ) Rat_ Ebi3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRLF1, IL13RA2, IL11RA, IL13RA1, CNTFR, IL2RG, CRLF2, IL31RA, IL3RA, IL6ST, IL12RB1, CSF3R, IL12RB2, GHR, CSF2RA, IL6R, IL27RA, IL23R, LIFR, OSMR, IL5RA, PRLR, LEPR |
| Tissue | placenta, spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7U7N (EM 3.47A ) |
| DBSNP | rs1803524 rs4740 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:9342359}. |
| Mouse PG classification | NA |
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