| Gene Information | |
|---|---|
| Gene Name | EPDR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 224 |
| Protein Names | Mammalian ependymin-related protein 1 (MERP-1) (Upregulated in colorectal cancer gene 1 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000086289 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UM22 |
| Gene Card | EPDR1 |
| Uniprot ID | Q9UM22 |
| Pfam | PF00811 |
| In ASD | no |
| Allosteric Prediction | no (-0.737662163) |
| Ortholog in Animals | Alpaca_ EPDR1 ( ortholog_one2one ) Dog_ EPDR1 ( ortholog_one2one ) GuineaPig_ EPDR1 ( ortholog_one2one ) Macaque_ EPDR1 ( ortholog_one2one ) Mouse_ Epdr1 ( ortholog_one2one ) Pig_ EPDR1 ( ortholog_one2one ) Rat_ Epdr1 ( ortholog_one2one ) Rabbit_ EPDR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Detected in brain, heart, skeletal muscle, kidney, testis, ovary and prostate. {ECO:0000269|PubMed:11749721}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6E7O (X-ray 3.00A ) 6E8N (X-ray 3.20A ) 6JLD (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Lysosome lumen {ECO:0000269|PubMed:30729188}. Secreted {ECO:0000269|PubMed:30729188}. Note=Lysosomal and also secreted. {ECO:0000269|PubMed:30729188}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |