| Gene Information | |
|---|---|
| Gene Name | NAT10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1025 |
| Protein Names | RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) (N-acetyltransferase-like protein) (hALP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000135372 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9H0A0 |
| Gene Card | NAT10 |
| Uniprot ID | Q9H0A0 |
| Pfam | PF13718; PF05127; PF08351; PF13725 |
| In ASD | no |
| Allosteric Prediction | no (-0.252153002) |
| Ortholog in Animals | Alpaca_ NAT10 ( ortholog_one2one ) Dog_ NAT10 ( ortholog_one2one ) GuineaPig_ NAT10 ( ortholog_one2one ) Macaque_ NAT10 ( ortholog_one2one ) Mouse_ Nat10 ( ortholog_one2one ) Pig_ NAT10 ( ortholog_one2one ) Rat_ Nat10 ( ortholog_one2one ) Rabbit_ NAT10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.453923(Rat);0.101695(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6VLA (NMR - ) 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) |
| DBSNP | rs2957516 rs36006049 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03211, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:14592445, ECO:0000269|PubMed:19303003, ECO:0000269|PubMed:24786082, ECO:0000269|PubMed:25653167, ECO:0000269|PubMed:30165671}. Midbody {ECO:0000255|HAMAP-Rule:MF_03211, ECO:0000269|PubMed:19303003}. Note=Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase. {ECO:0000269|PubMed:19303003}. |
| Mouse PG classification | NA |
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