| Gene Information | |
|---|---|
| Gene Name | NAPSA |
| Organism | Homo sapiens (Human) |
| Gene Length | 420 |
| Protein Names | Napsin-A (EC 3.4.23.-) (Aspartyl protease 4) (ASP4) (Asp 4) (Napsin-1) (TA01/TA02) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000131400 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O96009 |
| Gene Card | NAPSA |
| Uniprot ID | O96009 |
| Pfam | PF00026 |
| In ASD | no |
| Allosteric Prediction | no (-0.599340352) |
| Ortholog in Animals | Alpaca_ NAPSA ( ortholog_one2one ) Dog_ NAPSA ( ortholog_one2one ) GuineaPig_ NAPSA ( ortholog_one2one ) Macaque_ NAPSA ( ortholog_one2one ) Mouse_ Napsa ( ortholog_one2one ) Pig_ NAPSA ( ortholog_one2one ) Rat_ Napsa ( ortholog_one2one ) |
| Ohnologs | CTSD |
| Paralogs | PGC, BACE2, REN, CTSE, BACE1, CTSD, PGA5, PGA4, PGA3 |
| Tissue | lung |
| Tissue Specificity | Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs676314 rs11670727 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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