| Gene Information | |
|---|---|
| Gene Name | STX1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000099365 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | P61266 |
| Gene Card | STX1B |
| Uniprot ID | P61266 |
| Pfam | PF05739; PF00804 |
| In ASD | no |
| Allosteric Prediction | no (-0.560072474) |
| Ortholog in Animals | Alpaca_ STX1B ( ortholog_one2one ) Dog_ STX1B ( ortholog_one2one ) GuineaPig_ STX1B ( ortholog_one2one ) Macaque_ STX1B ( ortholog_one2one ) Mouse_ Stx1b ( ortholog_one2one ) Pig_ STX1B ( ortholog_one2one ) Rat_ Stx1b ( ortholog_one2one ) Rabbit_ STX1B ( ortholog_one2one ) |
| Ohnologs | STX1A, STX2, STX3 |
| Paralogs | STX19, STX11, STX16, STX12, STX5, STX17, STX7, TSNARE1, STX1A, STX2, STX4, STX3 |
| Tissue | brain, cerebral.cortex, substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.050500(Mouse);NULL(Rat);0.119021(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs724159974 rs727502806 |
| Subcellular location [CC] | [Isoform 1]: Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.; [Isoform 2]: Nucleus {ECO:0000269|PubMed:18691641}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18691641}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18691641}. Note=Colocalizes with Lamin A/C and NuMA in interphasic nuclei, and with NuMA and gamma-tubulin in the pericentrosomal region of the mitotic spindle in dividing cells. |
| Mouse PG classification | HPG |
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