| Gene Information | |
|---|---|
| Gene Name | NANOG |
| Organism | Homo sapiens (Human) |
| Gene Length | 305 |
| Protein Names | Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000111704 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H9S0 |
| Gene Card | NANOG |
| Uniprot ID | Q9H9S0 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-0.256893438) |
| Ortholog in Animals | Alpaca_ NANOG ( ortholog_one2many ) Mouse_ Nanog ( ortholog_one2many ) Pig_ NANOG ( ortholog_one2many ) Rat_ Nanog ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | VENTX, BSX, DLX2, DLX3, DLX5, DLX6, DLX1, DLX4, NANOGP8 |
| Tissue | NA |
| Tissue Specificity | Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and oocytes. {ECO:0000269|PubMed:12787504, ECO:0000269|PubMed:12787505, ECO:0000269|PubMed:14990856, ECO:0000269|PubMed:15982323, ECO:0000269|PubMed:16391521}. |
| Pharmacological Animal Models | 0.053204(Chimpanzee);0.104857(Mouse);0.003990(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KT0 (NMR - ) 4RBO (X-ray 3.30A ) |
| DBSNP | rs2889551 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:15983365}. |
| Mouse PG classification | NA |
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