| Gene Information | |
|---|---|
| Gene Name | NAGLU |
| Organism | Homo sapiens (Human) |
| Gene Length | 743 |
| Protein Names | Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] |
| Target Name | alpha-n-acetylglucosaminidase |
| Target Type | Successful target |
| Gene Age | 1488 ( ENSG00000108784 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P54802 |
| Gene Card | NAGLU |
| Uniprot ID | P54802 |
| Pfam | PF05089; PF12972; PF12971 |
| In ASD | no |
| Allosteric Prediction | no (-0.184431063) |
| Ortholog in Animals | Alpaca_ NAGLU ( ortholog_one2one ) Dog_ NAGLU ( ortholog_one2one ) GuineaPig_ NAGLU ( ortholog_one2one ) Macaque_ NAGLU ( ortholog_one2one ) Mouse_ Naglu ( ortholog_one2one ) Pig_ NAGLU ( ortholog_one2one ) Rat_ Naglu ( ortholog_one2one ) Rabbit_ NAGLU ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Liver, ovary, peripheral blood leukocytes, testis, prostate, spleen, colon, lung, placenta and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.15(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XWH (X-ray 2.32A ) |
| DBSNP | rs1460260015 rs867910252 rs104894599 rs1599253805 rs1276484671 rs1599253815 rs1555621454 rs758785463 rs753520553 rs770684838 rs747155746 rs104894601 rs1465855291 rs1392732615 rs1358994052 rs1305299665 rs104894600 rs749140168 rs768918822 rs368687817 rs796052122 rs574688121 rs768814260 rs114625063 rs1183634153 rs375103824 rs200909691 rs104894596 rs773054539 rs992677795 rs104894595 rs104894598 rs104894598 rs104894597 rs1215582852 rs148881970 rs1555622482 rs104894594 rs104894593 rs527236037 rs746006696 rs763299645 rs104894590 rs1364203992 rs86312 |
| Subcellular location [CC] | Lysosome. |
| Mouse PG classification | NA |
| click here to return to the previous page | |