| Gene Information | |
|---|---|
| Gene Name | UGT1A5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 534 |
| Protein Names | UDP-glucuronosyltransferase 1A5 (UGT1A5) (EC 2.4.1.17) (UDP-glucuronosyltransferase 1-5) (UDPGT 1-5) (UGT1*5) (UGT1-05) (UGT1.5) (UDP-glucuronosyltransferase 1-E) (UGT-1E) (UGT1E) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P35504 |
| Gene Card | UGT1A5 |
| Uniprot ID | P35504 |
| Pfam | PF00201 |
| In ASD | no |
| Allosteric Prediction | no (-0.148695973) |
| Ortholog in Animals | Mouse_ Ugt1a2 ( ortholog_many2many ) Mouse_ Ugt1a5 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | UGT2B15, UGT2B17, UGT2A3, UGT3A1, UGT8, UGT2B4, UGT2B7, UGT3A2, UGT1A1, UGT1A10, UGT1A8, UGT1A7, UGT1A9, UGT2A1, UGT2A2, UGT1A6, UGT2B10, UGT2B11, UGT2B28, UGT1A4, UGT1A3 |
| Tissue | NA |
| Tissue Specificity | Isoform 1 and isoform 2 are expressed in colon and small intestine. Neither isoform is expressed in liver, kidney or esophagus. {ECO:0000269|PubMed:18004212}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3755323 rs3755322 rs3755321 rs3755320 rs28946885 rs12475068 rs17862867 rs17862868 rs3892170 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P22309}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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