| Gene Information | |
|---|---|
| Gene Name | NACA |
| Organism | Homo sapiens (Human) |
| Gene Length | 215 |
| Protein Names | Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (allergen Hom s 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000196531 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13765 |
| Gene Card | NACA |
| Uniprot ID | Q13765 |
| Pfam | PF19026; PF01849 |
| In ASD | no |
| Allosteric Prediction | no (-0.49614799) |
| Ortholog in Animals | Dog_ NACA ( ortholog_one2one ) Macaque_ NACA ( ortholog_one2one ) Mouse_ Naca ( ortholog_one2one ) Rat_ Naca ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NACAD, NACA2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:16201836}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LKX (X-ray 2.50A ) 3MCB (X-ray 1.90A ) 3MCE (X-ray 2.40A ) 7QWQ (EM 2.83A ) 7QWR (EM 2.90A ) 7QWS (EM 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10982809, ECO:0000269|PubMed:12689679, ECO:0000269|PubMed:15299025, ECO:0000269|PubMed:20214399}. Nucleus {ECO:0000269|PubMed:12689679, ECO:0000269|PubMed:15299025, ECO:0000269|PubMed:20214399}. Note=The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus. {ECO:0000269|PubMed:10982809, ECO:0000269|PubMed:20214399}. |
| Mouse PG classification | NA |
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