Gene Information
Gene NameNAALADASEL
OrganismHomo sapiens (Human)
Gene Length740
Protein NamesAminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9UQQ1
Gene CardNAALADL1
Uniprot IDQ9UQQ1
PfamPF02225; PF04389; PF04253
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in small intestine (at protein level) (PubMed:25752612). Detected in ileum (PubMed:9388249). Detected in small intestine, spleen and testis. Isoform 2 and isoform 3 are found in the small intestine and colon (PubMed:10085079). {ECO:0000269|PubMed:10085079, ECO:0000269|PubMed:25752612, ECO:0000269|PubMed:9388249}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4TWE  (X-ray  1.75A 
DBSNP rs35422506  rs12223986  rs36053340 
Subcellular location [CC]Apical cell membrane {ECO:0000250|UniProtKB:O54697};
Single-pass type II membrane protein {ECO:0000250|UniProtKB:O54697}. Note=Ileal brush border membrane. {ECO:0000250|UniProtKB:O54697}.
Mouse PG classificationNA
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