| Gene Information | |
|---|---|
| Gene Name | IFT80 |
| Organism | Homo sapiens (Human) |
| Gene Length | 777 |
| Protein Names | Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000068885 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P2H3 |
| Gene Card | IFT80 |
| Uniprot ID | Q9P2H3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.249273974) |
| Ortholog in Animals | Alpaca_ IFT80 ( ortholog_one2one ) Dog_ IFT80 ( ortholog_one2one ) GuineaPig_ IFT80 ( ortholog_one2one ) Macaque_ IFT80 ( ortholog_one2one ) Mouse_ Ift80 ( ortholog_one2one ) Pig_ IFT80 ( ortholog_one2one ) Rat_ Ift80 ( ortholog_one2one ) Rabbit_ IFT80 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TRIM59 |
| Tissue | NA |
| Tissue Specificity | Isoform IFT80-L is widely expressed. {ECO:0000269|PubMed:18601909}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002240(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs137853115 rs6778728 rs137853116 |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Note=Basal body and ciliary axoneme. {ECO:0000250}. |
| Mouse PG classification | HPG |
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