| Gene Information | |
|---|---|
| Gene Name | N6AMT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 214 |
| Protein Names | Methyltransferase N6AMT1 (HemK methyltransferase family member 2) (M.HsaHemK2P) (Lysine N-methyltransferase 9) (EC 2.1.1.-) (Methylarsonite methyltransferase N6AMT1) (EC 2.1.1.-) (Protein N(5)-glutamine methyltransferase) (EC 2.1.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000156239 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9Y5N5 |
| Gene Card | N6AMT1 |
| Uniprot ID | Q9Y5N5 |
| Pfam | PF05175 |
| In ASD | no |
| Allosteric Prediction | no (-1.306981349) |
| Ortholog in Animals | Alpaca_ N6AMT1 ( ortholog_one2one ) GuineaPig_ N6AMT1 ( ortholog_one2one ) Macaque_ N6AMT1 ( ortholog_one2one ) Mouse_ N6amt1 ( ortholog_one2one ) Pig_ N6AMT1 ( ortholog_one2one ) Rat_ N6amt1 ( ortholog_one2one ) Rabbit_ N6AMT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HEMK1, ETFBKMT |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in parathyroid and pituitary glands, followed by adrenal gland and kidney, and lowest expression in leukocytes and mammary gland. {ECO:0000269|PubMed:21193388}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.002419(Rat);0.060000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6H1D (X-ray 1.94A ) 6H1E (X-ray 1.90A ) 6K0X (X-ray 2.20A ) 6KHS (X-ray 1.90A ) 6KMR (X-ray 2.00A ) 6KMS (X-ray 3.20A ) 6PED (X-ray 2.30A ) |
| DBSNP | rs1997607 rs2205447 rs2205446 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q6SKR2}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |