| Gene Information | |
|---|---|
| Gene Name | ARHGAP17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 881 |
| Protein Names | Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000140750 ) 3 ( ENSG00000288353 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q68EM7 |
| Gene Card | ARHGAP17 |
| Uniprot ID | Q68EM7 |
| Pfam | PF03114; PF00620 |
| In ASD | no |
| Allosteric Prediction | no (-0.435512242) |
| Ortholog in Animals | Alpaca_ ARHGAP17 ( ortholog_one2one ) Dog_ ARHGAP17 ( ortholog_one2one ) GuineaPig_ ARHGAP17 ( ortholog_one2one ) Macaque_ ARHGAP17 ( ortholog_one2one ) Mouse_ Arhgap17 ( ortholog_one2one ) Pig_ ARHGAP17 ( ortholog_one2one ) Rat_ Arhgap17 ( ortholog_one2one ) Rabbit_ ARHGAP17 ( ortholog_one2one ) |
| Ohnologs | ARHGAP44, SH3BP1 |
| Paralogs | ARHGAP44, SH3BP1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Expressed at higher level in heart and placenta. {ECO:0000269|PubMed:11431473}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Peripheral membrane protein. Cytoplasm. Cell junction, tight junction. Note=Associates with membranes and concentrates at sites of cell-cell contact. |
| Mouse PG classification | NA |
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