| Gene Information | |
|---|---|
| Gene Name | DYRK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000010219 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NR20 |
| Gene Card | DYRK4 |
| Uniprot ID | Q9NR20 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.992798497) |
| Ortholog in Animals | Alpaca_ DYRK4 ( ortholog_one2one ) Dog_ DYRK4 ( ortholog_one2one ) GuineaPig_ DYRK4 ( ortholog_one2one ) Macaque_ DYRK4 ( ortholog_one2one ) Mouse_ Dyrk4 ( ortholog_one2one ) Pig_ DYRK4 ( ortholog_one2one ) Rat_ Dyrk4 ( ortholog_one2one ) Rabbit_ DYRK4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CLK1, HIPK3, DYRK1B, HIPK1, CLK3, HIPK4, DYRK3, HIPK2, CLK4, DYRK2, DYRK1A, CLK2 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12306130 rs746486416 rs3741927 rs1801016 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:17292540}.; [Isoform 4]: Cytoplasm {ECO:0000269|PubMed:21127067}. Nucleus {ECO:0000269|PubMed:21127067}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |