| Gene Information | |
|---|---|
| Gene Name | MYRIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 859 |
| Protein Names | Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000170011 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NFW9 |
| Gene Card | MYRIP |
| Uniprot ID | Q8NFW9 |
| Pfam | PF02318; PF04698 |
| In ASD | no |
| Allosteric Prediction | no (-0.478876558) |
| Ortholog in Animals | Alpaca_ MYRIP ( ortholog_one2one ) Dog_ MYRIP ( ortholog_one2one ) Macaque_ MYRIP ( ortholog_one2one ) Mouse_ Myrip ( ortholog_one2one ) Pig_ MYRIP ( ortholog_one2one ) Rat_ Myrip ( ortholog_one2one ) Rabbit_ MYRIP ( ortholog_one2one ) |
| Ohnologs | MLPH |
| Paralogs | MOBP, MLPH |
| Tissue | NA |
| Tissue Specificity | Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs59923220 rs55785561 rs34800524 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8K3I4}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q7TNY7}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:Q7TNY7}. Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments. {ECO:0000250|UniProtKB:Q7TNY7}. |
| Mouse PG classification | NA |
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