| Gene Information | |
|---|---|
| Gene Name | CSTA |
| Organism | Homo sapiens (Human) |
| Gene Length | 98 |
| Protein Names | Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000121552 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P01040 |
| Gene Card | CSTA |
| Uniprot ID | P01040 |
| Pfam | PF00031 |
| In ASD | no |
| Allosteric Prediction | no (-0.999883504) |
| Ortholog in Animals | Alpaca_ CSTA ( ortholog_one2one ) Dog_ CSTA ( ortholog_one2one ) Macaque_ CSTA ( ortholog_one2one ) Mouse_ Cstdc5 ( ortholog_one2many ) Mouse_ Stfa2 ( ortholog_one2many ) Mouse_ Stfa2l1 ( ortholog_one2many ) Mouse_ Stfa1 ( ortholog_one2many ) Mouse_ Csta2 ( ortholog_one2many ) Mouse_ Csta1 ( ortholog_one2many ) Mouse_ Cstdc4 ( ortholog_one2many ) Mouse_ Cstdc6 ( ortholog_one2many ) Mouse_ Stfa3 ( ortholog_one2many ) Mouse_ Csta3 ( ortholog_one2many ) Rat_ Stfa3 ( ortholog_one2many ) Rat_ Csta ( ortholog_one2many ) Rat_ Stfa3l1 ( ortholog_one2many ) Rat_ Stfa2l1 ( ortholog_one2many ) Rat_ Stfa2l2 ( ortholog_one2many ) Rat_ Stfa2 ( ortholog_one2many ) Rabbit_ CSTA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CSTB |
| Tissue | esophagus.mucosa |
| Tissue Specificity | Expressed in the skin throughout the epidermis. {ECO:0000269|PubMed:21944047}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CYU (NMR - ) 1CYV (NMR - ) 1DVC (NMR - ) 1DVD (NMR - ) 1GD3 (NMR - ) 1GD4 (NMR - ) 1N9J (NMR - ) 1NB3 (X-ray 2.80A ) 1NB5 (X-ray 2.40A ) 3K9M (X-ray 2.61A ) 3KFQ (X-ray 1.99A ) 3KSE (X-ray 1.71A ) |
| DBSNP | rs34173813 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21944047}. |
| Mouse PG classification | NA |
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