Gene Information
Gene NameADRA2C
OrganismHomo sapiens (Human)
Gene Length462
Protein NamesAlpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)
Target Namealpha adrenergic receptor
Target TypeNA
Gene Age78 ( ENSG00000184160 )
Evolutionary StageEumetazoa
AlphaFoldDBP18825
Gene CardADRA2C
Uniprot IDP18825
PfamPF00001
In ASDyes
Allosteric Predictionyes (1.331540256)
Ortholog in AnimalsAlpaca_ ADRA2C ( ortholog_one2one )
Macaque_ ADRA2C ( ortholog_one2one )
Mouse_ Adra2c ( ortholog_one2one )
Pig_ ADRA2C ( ortholog_one2one )
Rat_ Adra2c ( ortholog_one2one )
OhnologsADRA2A
ParalogsOR56A4, ADRA2A, ADRB2, ADRA2B, OR56A1, OR56A3, OR56A5, DRD2, ADRA1B, ADRB3, ADRA1D, OR5T2, OR5T3, OR5T1, ADRA1A, GPR101, ADRB1, OR13F1
Tissueendometrium, oviduct, spleen
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6KUW  (X-ray  2.80A 
DBSNP NA 
Subcellular location [CC]Cell membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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