| Gene Information | |
|---|---|
| Gene Name | MMP17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 603 |
| Protein Names | Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP) |
| Target Name | matrix metalloproteinase-17 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000198598 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9ULZ9 |
| Gene Card | MMP17 |
| Uniprot ID | Q9ULZ9 |
| Pfam | PF00045; PF00413; PF01471 |
| In ASD | no |
| Allosteric Prediction | no (-0.221560071) |
| Ortholog in Animals | Alpaca_ MMP17 ( ortholog_one2one ) Dog_ MMP17 ( ortholog_one2one ) GuineaPig_ MMP17 ( ortholog_one2one ) Macaque_ MMP17 ( ortholog_one2one ) Mouse_ Mmp17 ( ortholog_one2one ) Pig_ MMP17 ( ortholog_one2one ) Rat_ Mmp17 ( ortholog_one2one ) |
| Ohnologs | MMP25, MMP11, MMP8, MMP20, MMP13, MMP3, MMP10, MMP1 |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP27, MMP25, MMP28, MMP13, MMP7, MMP20, MMP26, HPX, MMP8, MMP3, MMP11 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform Long]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | NA |
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