| Gene Information | |
|---|---|
| Gene Name | SLCO2A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 643 |
| Protein Names | Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2) |
| Target Name | prostaglandin transporter |
| Target Type | Patented-recorded target |
| Gene Age | 680 ( ENSG00000174640 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q92959 |
| Gene Card | SLCO2A1 |
| Uniprot ID | Q92959 |
| Pfam | PF07648; PF03137 |
| In ASD | no |
| Allosteric Prediction | yes (0.520770061) |
| Ortholog in Animals | Alpaca_ SLCO2A1 ( ortholog_one2one ) Dog_ SLCO2A1 ( ortholog_one2one ) GuineaPig_ SLCO2A1 ( ortholog_one2one ) Macaque_ SLCO2A1 ( ortholog_one2one ) Mouse_ Slco2a1 ( ortholog_one2one ) Pig_ SLCO2A1 ( ortholog_one2one ) Rat_ Slco2a1 ( ortholog_one2one ) Rabbit_ SLCO2A1 ( ortholog_one2one ) |
| Ohnologs | SLCO1A2, SLCO2B1, SLCO1C1 |
| Paralogs | SLCO5A1, SLCO6A1, SLCO4C1, SLCO4A1, SLCO2B1, SLCO1B1, SLCO1B3, SLCO1C1, SLCO1A2, SLCO3A1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Significant expression observed in ling, kidney, spleen, and heart. {ECO:0000269|PubMed:22331663}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3MRR (X-ray 1.60A ) |
| DBSNP | rs387907296 rs1376989560 rs555934769 rs774795340 rs387906806 rs34550074 rs387907295 rs146970901 rs779203269 |
| Subcellular location [CC] | Cell membrane {ECO:0000305|PubMed:8787677}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | LPG |
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