| Gene Information | |
|---|---|
| Gene Name | MYO5A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1855 |
| Protein Names | Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000197535 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y4I1 |
| Gene Card | MYO5A |
| Uniprot ID | Q9Y4I1 |
| Pfam | PF01843; PF00612; PF00063 |
| In ASD | no |
| Allosteric Prediction | yes (0.34017728) |
| Ortholog in Animals | Alpaca_ MYO5A ( ortholog_one2one ) Dog_ MYO5A ( ortholog_one2one ) GuineaPig_ MYO5A ( ortholog_one2one ) Macaque_ MYO5A ( ortholog_one2one ) Mouse_ Myo5a ( ortholog_one2one ) Pig_ MYO5A ( ortholog_one2one ) Rat_ Myo5a ( ortholog_one2one ) Rabbit_ MYO5A ( ortholog_one2one ) |
| Ohnologs | MYO5B |
| Paralogs | MYO3A, MYH10, TMF1, MYO7B, MYO1D, CCDC102B, MYH1, MYO19, MYO1C, MYH3, MYH7, MYO1A, MYO15A, MYH9, MYO18A, MYO1E, MYH14, MYH2, MYH15, MYO3B, CCDC102A, MYO1G, MYO1H, MYO18B, MYO5C, MYO9B, MYO7A, MYH7B, MYO5B, CGNL1, CGN, MYH11, MYO16, MYO10, MYH8, MYH6, MYO9A, MYO6, MYH4, CCDC158, MYO1B, MYO1F, MYH13 |
| Tissue | NA |
| Tissue Specificity | Detected in melanocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.034483(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4D07 (X-ray 1.85A ) 4J5L (X-ray 2.20A ) 4LLI (X-ray 2.20A ) 4LX1 (X-ray 1.87A ) 4LX2 (X-ray 1.50A ) 5JCY (X-ray 1.80A ) 5JCZ (X-ray 2.06A ) |
| DBSNP | rs16964944 rs1058219 rs9282796 |
| Subcellular location [CC] | NA |
| Mouse PG classification | HPG |
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