| Gene Information | |
|---|---|
| Gene Name | RASGEF1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 473 |
| Protein Names | Ras-GEF domain-containing family member 1B (GPI gamma-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000138670 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q0VAM2 |
| Gene Card | RASGEF1B |
| Uniprot ID | Q0VAM2 |
| Pfam | PF00617; PF00618 |
| In ASD | no |
| Allosteric Prediction | no (-1.276804606) |
| Ortholog in Animals | Alpaca_ RASGEF1B ( ortholog_one2one ) Dog_ RASGEF1B ( ortholog_one2one ) Macaque_ RASGEF1B ( ortholog_one2one ) Mouse_ Rasgef1b ( ortholog_one2one ) Pig_ RASGEF1B ( ortholog_one2one ) Rat_ Rasgef1b ( ortholog_one2one ) Rabbit_ RASGEF1B ( ortholog_one2one ) |
| Ohnologs | RASGEF1C, RASGEF1A |
| Paralogs | RALGDS, RASGEF1A, RASGRF2, RASGRP3, SOS2, RAPGEF3, RAPGEF6, RASGRF1, RAPGEF2, RGL1, RAPGEF1, RASGRP2, RGL2, SOS1, RGL3, RALGPS1, RALGPS2, RAPGEF4, RGL4, RASGRP4, RAPGEFL1, RAPGEF5, RASGRP1, RASGEF1C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome {ECO:0000250}. Late endosome {ECO:0000250}. Midbody {ECO:0000269|PubMed:23894443}. Note=May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase. {ECO:0000250}. |
| Mouse PG classification | NA |
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