Gene Information
Gene NameMYL9
OrganismHomo sapiens (Human)
Gene Length172
Protein NamesMyosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000101335 )
Evolutionary StageOpisthokonta
AlphaFoldDBP24844
Gene CardMYL9
Uniprot IDP24844
PfamPF13405; PF13833
In ASDno
Allosteric Predictionno (-0.999897332)
Ortholog in AnimalsAlpaca_ MYL9 ( ortholog_one2one )
Dog_ MYL9 ( ortholog_one2many )
GuineaPig_ MYL9 ( ortholog_one2one )
Macaque_ MYL9 ( ortholog_one2one )
Mouse_ Myl9 ( ortholog_one2one )
Pig_ MYL9 ( ortholog_one2one )
Rat_ Myl9 ( ortholog_one2one )
Rabbit_ MYL9 ( ortholog_one2one )
OhnologsMYL12A, MYL12B
ParalogsMYL12A, MYL12B, MYL11, MYL7, MYL5, MYL2, MYL10
TissueNA
Tissue SpecificitySmooth muscle tissues and in some, but not all, nonmuscle cells. {ECO:0000269|PubMed:2526655}.
Pharmacological Animal Models0.000730(Chimpanzee);0.342797(Mouse);0.001000(Rat);0.082143(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9CQ19}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9CQ19}. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts. {ECO:0000250|UniProtKB:Q9CQ19}.
Mouse PG classificationNA
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