| Gene Information | |
|---|---|
| Gene Name | RHOC |
| Organism | Homo sapiens (Human) |
| Gene Length | 193 |
| Protein Names | Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000155366 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P08134 |
| Gene Card | RHOC |
| Uniprot ID | P08134 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.273499061) |
| Ortholog in Animals | Alpaca_ RHOC ( ortholog_one2one ) Dog_ RHOC ( ortholog_one2one ) GuineaPig_ RHOC ( ortholog_one2one ) Mouse_ Rhoc ( ortholog_one2one ) Pig_ RHOC ( ortholog_one2one ) Rat_ Rhoc ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RHOB, RHOA, RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOJ, RHOV, RHOQ, RHOBTB2, RND2, RND3, RHOD, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.013333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Z2C (X-ray 3.00A ) 2GCN (X-ray 1.85A ) 2GCO (X-ray 1.40A ) 2GCP (X-ray 2.15A ) |
| DBSNP | rs11538959 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cleavage furrow {ECO:0000269|PubMed:16236794}. Note=Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. |
| Mouse PG classification | NA |
| click here to return to the previous page | |