| Gene Information | |
|---|---|
| Gene Name | MYH7B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1983 |
| Protein Names | Myosin-7B (Antigen MLAA-21) (Myosin cardiac muscle beta chain) (Myosin heavy chain 7B, cardiac muscle beta isoform) (Slow A MYH14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000078814 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | A7E2Y1 |
| Gene Card | MYH7B |
| Uniprot ID | A7E2Y1 |
| Pfam | PF00063; PF02736; PF01576 |
| In ASD | no |
| Allosteric Prediction | no (-0.541956929) |
| Ortholog in Animals | Alpaca_ MYH7B ( ortholog_one2one ) Dog_ MYH7B ( ortholog_one2one ) GuineaPig_ MYH7B ( ortholog_one2one ) Macaque_ MYH7B ( ortholog_one2one ) Mouse_ Myh7b ( ortholog_one2one ) Pig_ MYH7B ( ortholog_one2one ) Rat_ Myh7b ( ortholog_one2one ) Rabbit_ MYH7B ( ortholog_one2one ) |
| Ohnologs | MYH13, MYH7, MYH1, MYH3, MYH2, MYH8, MYH6 |
| Paralogs | MYO3A, MYH10, TMF1, MYO7B, MYO1D, CCDC102B, MYH1, MYO19, MYO1C, MYH3, MYH7, MYO1A, MYO15A, MYH9, MYO18A, MYO1E, MYH14, MYH2, MYH15, MYO3B, CCDC102A, MYO5A, MYO1G, MYO1H, MYO18B, MYO5C, MYO9B, MYO7A, MYO5B, CGNL1, CGN, MYH11, MYO16, MYO10, MYH8, MYH6, MYO9A, MYO6, MYH4, CCDC158, MYO1B, MYO1F, MYH13 |
| Tissue | heart, skeletal.muscle, atrium, left.ventricle |
| Tissue Specificity | Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly lower expression was detected in ovary and kidney, and intermediate expression was detected in lung, pancreas, spleen and liver. {ECO:0000269|PubMed:10819331}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17092199 rs754511 rs3746442 rs2425015 rs3746435 rs6060147 rs6060148 rs7273482 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:15755502}; Peripheral membrane protein {ECO:0000269|PubMed:15755502}. |
| Mouse PG classification | NA |
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