| Gene Information | |
|---|---|
| Gene Name | MYH3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1940 |
| Protein Names | Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000109063 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P11055 |
| Gene Card | MYH3 |
| Uniprot ID | P11055 |
| Pfam | PF00063; PF02736; PF01576 |
| In ASD | no |
| Allosteric Prediction | no (-0.113711273) |
| Ortholog in Animals | Alpaca_ MYH3 ( ortholog_one2one ) Dog_ MYH3 ( ortholog_one2one ) GuineaPig_ MYH3 ( ortholog_one2one ) Macaque_ MYH3 ( ortholog_one2one ) Mouse_ Myh3 ( ortholog_one2one ) Pig_ MYH3 ( ortholog_one2one ) Rat_ Myh3 ( ortholog_one2one ) |
| Ohnologs | MYH7B |
| Paralogs | MYO3A, MYH10, TMF1, MYO7B, MYO1D, CCDC102B, MYH1, MYO19, MYO1C, MYH7, MYO1A, MYO15A, MYH9, MYO18A, MYO1E, MYH14, MYH2, MYH15, MYO3B, CCDC102A, MYO5A, MYO1G, MYO1H, MYO18B, MYO5C, MYO9B, MYO7A, MYH7B, MYO5B, CGNL1, CGN, MYH11, MYO16, MYO10, MYH8, MYH6, MYO9A, MYO6, MYH4, CCDC158, MYO1B, MYO1F, MYH13 |
| Tissue | prostate, testis |
| Tissue Specificity | Expressed in fetal bone, thymus, placenta, heart, brain, and liver. {ECO:0000269|PubMed:25957469}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121913619 rs121913623 rs1555527166 rs1597490381 rs1567560080 rs139480342 rs1567559562 rs121913621 rs121913622 rs1597488252 rs1597488038 rs121913618 rs121913617 rs121913620 rs34088014 rs796051884 rs12941197 rs2285477 rs35230241 rs1567553806 rs1446303362 rs34165480 |
| Subcellular location [CC] | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. |
| Mouse PG classification | NA |
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