| Gene Information | |
|---|---|
| Gene Name | SERPINB5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5) |
| Target Name | serpin b5 |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000206075 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P36952 |
| Gene Card | SERPINB5 |
| Uniprot ID | P36952 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | yes (0.350195293) |
| Ortholog in Animals | Alpaca_ SERPINB5 ( ortholog_one2one ) Dog_ SERPINB5 ( ortholog_one2one ) Macaque_ SERPINB5 ( ortholog_one2one ) Mouse_ Serpinb5 ( ortholog_one2one ) Pig_ SERPINB5 ( ortholog_one2one ) Rat_ Serpinb5 ( ortholog_one2one ) Rabbit_ SERPINB5 ( ortholog_one2one ) |
| Ohnologs | SERPINB1, SERPINB6 |
| Paralogs | SERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | tongue, zone.of.skin, esophagus.mucosa, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Normal mammary epithelial cells. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WZ9 (X-ray 2.10A ) 1XQG (X-ray 3.10A ) 1XQJ (X-ray 3.10A ) 1XU8 (X-ray 2.80A ) |
| DBSNP | rs2289519 rs2289520 rs1455555 |
| Subcellular location [CC] | Secreted, extracellular space. |
| Mouse PG classification | NA |
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