| Gene Information | |
|---|---|
| Gene Name | MYCN |
| Organism | Homo sapiens (Human) |
| Gene Length | 464 |
| Protein Names | N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000134323 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P04198 |
| Gene Card | MYCN |
| Uniprot ID | P04198 |
| Pfam | PF00010; PF01056 |
| In ASD | no |
| Allosteric Prediction | yes (0.501762024) |
| Ortholog in Animals | Alpaca_ MYCN ( ortholog_one2one ) Dog_ MYCN ( ortholog_one2one ) GuineaPig_ MYCN ( ortholog_one2one ) Macaque_ MYCN ( ortholog_one2one ) Mouse_ Mycs ( ortholog_one2one ) Pig_ MYCN ( ortholog_one2one ) Rat_ Mycs ( ortholog_one2one ) |
| Ohnologs | MYC, MYCL |
| Paralogs | MYCL, MYC |
| Tissue | NA |
| Tissue Specificity | Expressed in the neuronal cells of the cerebrum, neuroblastomas and thyroid tumors (at protein level). {ECO:0000269|PubMed:24391509}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5G1X (X-ray 1.72A ) |
| DBSNP | rs104893646 rs104893647 rs104893648 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | LPG |
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