| Gene Information | |
|---|---|
| Gene Name | MYC |
| Organism | Homo sapiens (Human) |
| Gene Length | 439 |
| Protein Names | Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) |
| Target Name | myc messenger rna |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000136997 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P01106 |
| Gene Card | MYC |
| Uniprot ID | P01106 |
| Pfam | PF00010; PF02344; PF01056 |
| In ASD | no |
| Allosteric Prediction | yes (1.070922115) |
| Ortholog in Animals | Alpaca_ MYC ( ortholog_one2one ) Dog_ MYC ( ortholog_one2one ) GuineaPig_ MYC ( ortholog_one2one ) Macaque_ MYC ( ortholog_one2one ) Mouse_ Bmyc ( ortholog_one2many ) Mouse_ Myc ( ortholog_one2many ) Pig_ MYC ( ortholog_one2one ) Rat_ Bmyc ( ortholog_one2many ) Rat_ Myc ( ortholog_one2many ) Rabbit_ MYC ( ortholog_one2one ) |
| Ohnologs | MYCL, MYCN |
| Paralogs | MYCN, MYCL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A93 (NMR - ) 1EE4 (X-ray 2.10A ) 1MV0 (NMR - ) 1NKP (X-ray 1.80A ) 2A93 (NMR - ) 2OR9 (X-ray 2.70A ) 4Y7R (X-ray 1.90A ) 5I4Z (X-ray 1.95A ) 5I50 (X-ray 2.70A ) 6C4U (X-ray 2.60A ) 6E16 (X-ray 2.40A ) 6E24 (X-ray 3.00A ) 6G6J (X-ray 2.25A ) 6G6K (X-ray 1.35A ) 6G6L (X-ray 2.20A ) 7T1Y (X-ray 2.55A ) 7T1Z (X-ray 2.77A ) |
| DBSNP | rs4645959 rs121918684 rs28933407 rs121918685 rs121918683 rs4645960 rs4645961 rs4645968 |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:17558397}. Nucleus, nucleolus {ECO:0000269|PubMed:17558397, ECO:0000269|PubMed:25775507}. |
| Mouse PG classification | NA |
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