| Gene Information | |
|---|---|
| Gene Name | MYBPHL |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Myosin-binding protein H-like |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000221986 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | A2RUH7 |
| Gene Card | MYBPHL |
| Uniprot ID | A2RUH7 |
| Pfam | PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | no (-1.76288941) |
| Ortholog in Animals | Alpaca_ MYBPHL ( ortholog_one2one ) Dog_ MYBPHL ( ortholog_one2one ) GuineaPig_ MYBPHL ( ortholog_one2one ) Macaque_ MYBPHL ( ortholog_one2one ) Mouse_ Mybphl ( ortholog_one2one ) Pig_ MYBPHL ( ortholog_one2one ) Rat_ Mybphl ( ortholog_one2one ) Rabbit_ MYBPHL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MYOM1, MYBPC1, MYBPC2, MYOM3, MYBPH, MYOM2, FNDC3A, MYBPC3, OBSL1, IGSF22, FNDC3B |
| Tissue | heart, left.atrium, mitral.valve, atrium |
| Tissue Specificity | Expressed in heart, with higher expression in the atria. {ECO:0000269|PubMed:28778945, ECO:0000269|PubMed:31292467}.; [Isoform 1]: Expressed in left atrium and ventricle, arteria mammaria interna and skeletal muscle. {ECO:0000269|PubMed:31292467}.; [Isoform 2]: Expressed specifically en the left atrium. {ECO:0000269|PubMed:31292467}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs629001 |
| Subcellular location [CC] | Cytoplasm, myofibril, sarcomere {ECO:0000305|PubMed:28778945}. |
| Mouse PG classification | NA |
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