| Gene Information | |
|---|---|
| Gene Name | MX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 715 |
| Protein Names | Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (Myxovirus resistance protein 2) (p78-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000183486 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P20592 |
| Gene Card | MX2 |
| Uniprot ID | P20592 |
| Pfam | PF01031; PF00350; PF02212 |
| In ASD | no |
| Allosteric Prediction | no (-0.425625282) |
| Ortholog in Animals | Alpaca_ MX1 ( ortholog_one2one ) Dog_ MX1 ( ortholog_one2one ) Macaque_ MX2 ( ortholog_one2one ) Pig_ MX2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DNM1L, DNM2, OPA1, DNM3, MX1, DNM1 |
| Tissue | whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WHJ (X-ray 3.20A ) 4X0R (X-ray 2.90A ) 5UOT (EM 4.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15184662}. Nucleus {ECO:0000269|PubMed:15184662}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:15184662}. Note=Localization to nuclear pores requires GTP-binding. |
| Mouse PG classification | NA |
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