| Gene Information | |
|---|---|
| Gene Name | MVK |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Mevalonate kinase (MK) (EC 2.7.1.36) |
| Target Name | mevalonate kinase |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000110921 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q03426 |
| Gene Card | MVK |
| Uniprot ID | Q03426 |
| Pfam | PF08544; PF00288 |
| In ASD | no |
| Allosteric Prediction | yes (0.19832446) |
| Ortholog in Animals | Alpaca_ MVK ( ortholog_one2one ) Dog_ MVK ( ortholog_one2one ) GuineaPig_ MVK ( ortholog_one2one ) Macaque_ MVK ( ortholog_one2one ) Mouse_ Mvk ( ortholog_one2one ) Pig_ MVK ( ortholog_one2one ) Rat_ Mvk ( ortholog_one2one ) Rabbit_ MVK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GALK2, GALK1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2R3V (X-ray 2.50A ) |
| DBSNP | rs11544299 rs104895295 rs104895335 rs104895296 rs397514571 rs7957619 rs104895336 rs104895297 rs104895298 rs747116992 rs104895300 rs104895337 rs104895301 rs104895325 rs104895303 rs104895314 rs104895339 rs397514570 rs104895315 rs104895316 rs104895316 rs104895304 rs121917789 rs104895305 rs104895319 rs104895308 rs104895317 rs11614976 rs104895342 rs398122911 rs971159663 rs104895340 rs28934897 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14730012}. Peroxisome {ECO:0000250|UniProtKB:P17256}. |
| Mouse PG classification | NA |
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