| Gene Information | |
|---|---|
| Gene Name | MUTYH |
| Organism | Homo sapiens (Human) |
| Gene Length | 546 |
| Protein Names | Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000132781 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UIF7 |
| Gene Card | MUTYH |
| Uniprot ID | Q9UIF7 |
| Pfam | PF00633; PF00730; PF14815 |
| In ASD | no |
| Allosteric Prediction | no (-0.129753807) |
| Ortholog in Animals | Alpaca_ MUTYH ( ortholog_one2one ) Dog_ MUTYH ( ortholog_one2one ) GuineaPig_ MUTYH ( ortholog_one2one ) Macaque_ MUTYH ( ortholog_one2one ) Mouse_ Mutyh ( ortholog_one2one ) Pig_ MUTYH ( ortholog_one2one ) Rat_ Mutyh ( ortholog_one2one ) Rabbit_ MUTYH ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NTHL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.12(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X51 (NMR - ) 3N5N (X-ray 2.30A ) |
| DBSNP | rs79777494 rs3219484 rs75321043 rs1140507 rs587780746 rs730881832 rs777184451 rs34612342 rs747993448 rs143353451 rs533899702 rs750592289 rs754155145 rs768553551 rs200872702 rs11545695 rs200165598 rs1057517765 rs34126013 rs200495564 rs140342925 rs587780749 rs587782885 rs769237459 rs876659676 rs730881833 rs374950566 rs138089183 rs587781810 rs3219489 rs199742231 rs35352891 rs1060501335 rs36053993 rs529008617 rs121908382 rs121908383 rs144079536 rs150792276 rs587782120 rs200844166 rs192816572 rs767747402 rs587782263 rs587782228 rs3219494 rs140118273 rs587778542 rs374655042 rs3219496 rs3219497 rs151196169 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:25820570}. Mitochondrion {ECO:0000250|UniProtKB:Q99P21}. |
| Mouse PG classification | NA |
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