Gene Information
Gene NameMUT
OrganismHomo sapiens (Human)
Gene Length750
Protein NamesMethylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase)
Target Namemethylmalonyl-coa mutase
Target TypeSuccessful target
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP22033
Gene CardMMUT
Uniprot IDP22033
PfamPF02310; PF01642
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2XIJ  (X-ray  1.95A  )  2XIQ  (X-ray  1.95A  )  3BIC  (X-ray  2.60A  ) 
DBSNP rs115923556  rs769348060  rs1554160986  rs121918251  rs727504022  rs535411418  rs190834116  rs864309735  rs121918249  rs121918257  rs483352778  rs1461110052  rs796052005  rs879253827  rs879253828  rs941483851  rs941483851  rs879253829  rs1554160730  rs1300547552  rs757000253  rs864309733  rs148331800  rs879253830  rs200908035  rs1561959114  rs760782399  rs778702777  rs879253831  rs121918258  rs121918258  rs1446389693  rs121918256  rs770810987  rs879253833  rs864309736  rs12175488  rs796052007  rs879253835  rs761477436  rs1179778233  rs1554160246  rs1085307929  rs864309734  rs781474200  rs780387525  rs879253837  rs758577372  rs796052002  rs965316043  rs1026703654  rs1407914109  rs563776413  rs864309737  rs772552898  rs564069299  rs368790885  rs121918250  rs1554159937  rs866933356  rs766010704  rs879253840  rs879253842  rs533755473  rs769922244  rs753288303  rs2229385  rs864309738  rs1141321  rs760183775  rs879253845  rs1238333040  rs775593146  rs1554158951  rs9473556  rs1554158777  rs1302409621  rs765284825  rs1554158775  rs879253846  rs121918254  rs768521956  rs879253847  rs982110849  rs372486357  rs143023066  rs200055428  rs781501004  rs865815395  rs747897332  rs766721811  rs1360470463  rs8589  rs1164271240  rs147094927  rs864309739  rs777758903  rs140600746  rs121918255  rs121918252  rs755077681  rs753461919 
Subcellular location [CC]Mitochondrion matrix {ECO:0000269|PubMed:24458}. Mitochondrion {ECO:0000269|PubMed:28943303}. Cytoplasm {ECO:0000269|PubMed:28943303}.
Mouse PG classificationNA
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