| Gene Information | |
|---|---|
| Gene Name | MUPCDH |
| Organism | Homo sapiens (Human) |
| Gene Length | 845 |
| Protein Names | Cadherin-related family member 5 (Mu-protocadherin) (Mucin and cadherin-like protein) (Mucin-like protocadherin) (MLPCDH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HBB8 |
| Gene Card | CDHR5 |
| Uniprot ID | Q9HBB8 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in adult small intestine and colon. Isoform 2 is highly expressed in fetal liver (PubMed:12167596). Expressed in duodenum with higher expression in enterocytes along the villus axis and lower expression in crypts (at protein level) (PubMed:24725409). {ECO:0000269|PubMed:12167596, ECO:0000269|PubMed:24725409}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6OAE (X-ray 1.90A ) |
| DBSNP | rs2740374 rs2246614 rs2306066 rs2740375 rs2740379 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:24725409}; Single-pass type I membrane protein {ECO:0000269|PubMed:24725409}. Cell projection, microvillus membrane {ECO:0000269|PubMed:24725409}; Single-pass type I membrane protein {ECO:0000269|PubMed:24725409}. |
| Mouse PG classification | NA |
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