| Gene Information | |
|---|---|
| Gene Name | MUC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2439 |
| Protein Names | Mucin-6 (MUC-6) (Gastric mucin-6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000184956 ) 3 ( ENSG00000283350 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6W4X9 |
| Gene Card | MUC6 |
| Uniprot ID | Q6W4X9 |
| Pfam | PF08742; PF01826; PF00094 |
| In ASD | no |
| Allosteric Prediction | no (-0.842682518) |
| Ortholog in Animals | Alpaca_ MUC6 ( ortholog_one2one ) Dog_ MUC6 ( ortholog_one2one ) Mouse_ Muc6 ( ortholog_one2one ) Pig_ MUC6 ( ortholog_one2one ) Rat_ Muc6 ( ortholog_one2one ) |
| Ohnologs | VWF |
| Paralogs | CHRDL1, MUC5B, KCP, CHRDL2, CHRD, VWF, VWCE, OTOGL, MUC5AC, OTOG, ZAN, BMPER, TECTA, FCGBP, CRIM1, MUC2, MUC19, VWC2L, VWC2 |
| Tissue | stomach, seminal.vesicle, vas.deferens, pancreas |
| Tissue Specificity | Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct. {ECO:0000269|PubMed:10209489, ECO:0000269|PubMed:10330458, ECO:0000269|PubMed:11988092, ECO:0000269|PubMed:15280409, ECO:0000269|PubMed:9422745}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10736904 rs35549382 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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