| Gene Information | |
|---|---|
| Gene Name | MUC5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 5654 |
| Protein Names | Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | MUC5AC |
| Uniprot ID | P98088 |
| Pfam | PF08742; PF13330; PF01826; PF00094 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. {ECO:0000269|PubMed:14535999, ECO:0000269|PubMed:7513696}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5AJN (X-ray 1.67A ) 5AJO (X-ray 1.48A ) 5AJP (X-ray 1.65A ) |
| DBSNP | rs1132436 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:14718370, ECO:0000269|PubMed:31732694}. |
| Mouse PG classification | NA |
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