| Gene Information | |
|---|---|
| Gene Name | CORO1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 461 |
| Protein Names | Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000102879 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P31146 |
| Gene Card | CORO1A |
| Uniprot ID | P31146 |
| Pfam | PF08953; PF08954; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.765958679) |
| Ortholog in Animals | Alpaca_ CORO1A ( ortholog_one2one ) Dog_ CORO1A ( ortholog_one2one ) GuineaPig_ CORO1A ( ortholog_one2one ) Macaque_ CORO1A ( ortholog_one2one ) Mouse_ Coro1a ( ortholog_one2one ) Pig_ CORO1A ( ortholog_one2one ) Rat_ Coro1a ( ortholog_one2one ) Rabbit_ CORO1A ( ortholog_one2one ) |
| Ohnologs | CORO6, CORO2B, CORO2A, CORO1C, CORO1B |
| Paralogs | CORO1C, CORO7, CORO6, CORO1B, CORO2B, CORO2A |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs397514755 rs1804109 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Note=In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity). {ECO:0000250}. |
| Mouse PG classification | LPG |
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