Gene Information
Gene NameCDT1
OrganismHomo sapiens (Human)
Gene Length546
Protein NamesDNA replication factor Cdt1 (Double parked homolog) (DUP)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000167513 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9H211
Gene CardCDT1
Uniprot IDQ9H211
PfamPF08839; PF16679
In ASDno
Allosteric Predictionno (-0.581314065)
Ortholog in AnimalsAlpaca_ CDT1 ( ortholog_one2one )
Dog_ CDT1 ( ortholog_one2one )
GuineaPig_ CDT1 ( ortholog_one2one )
Macaque_ CDT1 ( ortholog_one2one )
Mouse_ Cdt1 ( ortholog_one2one )
Pig_ CDT1 ( ortholog_one2one )
Rat_ Cdt1 ( ortholog_one2one )
Rabbit_ CDT1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuebone.marrow, brain
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002692(Rat);0.065217(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2LE8  (NMR  2WVR  (X-ray  3.30A  6QCG  (X-ray  3.40A 
DBSNP rs387906918  rs779871947  rs3218725  rs3218727  rs507329  rs480727  rs200672589  rs3218729  rs387906917  rs200652608  rs3218721 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:11125146, ECO:0000269|PubMed:26842564}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:22581055}. Note=Transiently localizes to kinetochores during prometaphase and metaphase. {ECO:0000269|PubMed:22581055}.
Mouse PG classificationNA
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