| Gene Information | |
|---|---|
| Gene Name | IKZF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 526 |
| Protein Names | Zinc finger protein Helios (Ikaros family zinc finger protein 2) |
| Target Name | zinc finger protein helios |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000030419 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UKS7 |
| Gene Card | IKZF2 |
| Uniprot ID | Q9UKS7 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.032176344) |
| Ortholog in Animals | Alpaca_ IKZF2 ( ortholog_one2one ) Dog_ IKZF2 ( ortholog_one2one ) GuineaPig_ IKZF2 ( ortholog_one2one ) Macaque_ IKZF2 ( ortholog_one2one ) Mouse_ Ikzf2 ( ortholog_one2one ) Pig_ IKZF2 ( ortholog_one2one ) Rat_ Ikzf2 ( ortholog_one2one ) Rabbit_ IKZF2 ( ortholog_one2one ) |
| Ohnologs | IKZF4, IKZF3, IKZF1 |
| Paralogs | ZNF613, ZNF649, ZNF821, IKZF1, ZNF567, ZNF639, ZNF382, IKZF4, IKZF3, ZNF350, ZNF564 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LPS (X-ray 3.78A ) |
| DBSNP | rs16849611 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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