| Gene Information | |
|---|---|
| Gene Name | CDH17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 832 |
| Protein Names | Cadherin-17 (Intestinal peptide-associated transporter HPT-1) (Liver-intestine cadherin) (LI-cadherin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000079112 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q12864 |
| Gene Card | CDH17 |
| Uniprot ID | Q12864 |
| Pfam | PF00028 |
| In ASD | no |
| Allosteric Prediction | yes (0.015076359) |
| Ortholog in Animals | Alpaca_ CDH17 ( ortholog_one2one ) Dog_ CDH17 ( ortholog_one2one ) GuineaPig_ CDH17 ( ortholog_one2one ) Macaque_ CDH17 ( ortholog_one2one ) Mouse_ Cdh17 ( ortholog_one2one ) Pig_ CDH17 ( ortholog_one2one ) Rat_ Cdh17 ( ortholog_one2one ) Rabbit_ CDH17 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, CDH19, PCDH9, CDH3, PCDH11Y, PCDH11X, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH6, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | colon, duodenum, small.intestine, rectum, small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. {ECO:0000269|PubMed:8153632}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ULM (X-ray 2.15A ) 7CYM (X-ray 2.70A ) 7EV1 (X-ray 1.38A ) |
| DBSNP | rs2243518 rs1131829 rs1051623 rs1051624 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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