| Gene Information | |
|---|---|
| Gene Name | MTG16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 653 |
| Protein Names | Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75081 |
| Gene Card | CBFA2T3 |
| Uniprot ID | O75081 |
| Pfam | PF08788; PF07531; PF01753 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with higher expression in heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes. Expressed in hematopoietic cells (at protein level). {ECO:0000269|PubMed:15231665, ECO:0000269|PubMed:9596646, ECO:0000269|PubMed:9790752}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs745972870 rs1053526 rs774310781 rs553618592 |
| Subcellular location [CC] | [Isoform 1]: Nucleus, nucleolus. Note=The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm.; [Isoform 2]: Nucleus, nucleoplasm {ECO:0000269|PubMed:11823486}. Golgi apparatus membrane {ECO:0000269|PubMed:11823486}. |
| Mouse PG classification | NA |
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