| Gene Information | |
|---|---|
| Gene Name | PTTG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 202 |
| Protein Names | Securin-2 (Pituitary tumor-transforming gene 2 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000250254 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NZH5 |
| Gene Card | PTTG2 |
| Uniprot ID | Q9NZH5 |
| Pfam | PF04856 |
| In ASD | no |
| Allosteric Prediction | no (-0.819966905) |
| Ortholog in Animals | Alpaca_ PTTG2 ( ortholog_one2one ) Dog_ PTTG1 ( ortholog_one2many ) Mouse_ Pttg1 ( ortholog_one2many ) Rat_ Pttg1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | PTTG1 |
| Tissue | NA |
| Tissue Specificity | Expressed at low levels in the pituitary, liver, spleen, prostate, testis, ovary, small intestine and colon. Also expressed in various pituitary, testicular, liver and ovarian tumors. {ECO:0000269|PubMed:10084610, ECO:0000269|PubMed:10806349}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6811863 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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