| Gene Information | |
|---|---|
| Gene Name | MTF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 753 |
| Protein Names | Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1) |
| Target Name | metallothionein |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000188786 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14872 |
| Gene Card | MTF1 |
| Uniprot ID | Q14872 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.304171403) |
| Ortholog in Animals | Alpaca_ MTF1 ( ortholog_one2one ) Dog_ MTF1 ( ortholog_one2one ) GuineaPig_ MTF1 ( ortholog_one2one ) Macaque_ MTF1 ( ortholog_one2one ) Mouse_ Mtf1 ( ortholog_one2one ) Pig_ MTF1 ( ortholog_one2one ) Rat_ Mtf1 ( ortholog_one2one ) Rabbit_ MTF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZNF575, ZNF276, HIC1, ZNF653, ZNF362, ZNF410, PATZ1, PRDM1, HIC2, ZNF76, ZFP91, PRDM6, ZNF296, ZBTB1, SNAI3, SNAI2, ZBTB20, ZNF281, MAZ, ZBTB18, ZNF143, ZBTB16, SNAI1, ZNF148, ZBTB32, ZBTB45, ZBTB7C, ZBTB42, ZNF451, ZNF692, PRDM14, VEZF1, SCRT2, SCRT1, ZNF384, PRDM10 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:8065932}. Cytoplasm {ECO:0000250|UniProtKB:Q07243}. Note=Translocation to the nucleus is induced by metals. {ECO:0000250|UniProtKB:Q07243}. |
| Mouse PG classification | NA |
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