| Gene Information | |
|---|---|
| Gene Name | MTF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1121 |
| Protein Names | Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein) |
| Target Name | metallothionein |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000188786 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q01538 |
| Gene Card | MYT1 |
| Uniprot ID | Q01538 |
| Pfam | PF08474; PF01530 |
| In ASD | no |
| Allosteric Prediction | no (-1.304171403) |
| Ortholog in Animals | Alpaca_ MTF1 ( ortholog_one2one ) Dog_ MTF1 ( ortholog_one2one ) GuineaPig_ MTF1 ( ortholog_one2one ) Macaque_ MTF1 ( ortholog_one2one ) Mouse_ Mtf1 ( ortholog_one2one ) Pig_ MTF1 ( ortholog_one2one ) Rat_ Mtf1 ( ortholog_one2one ) Rabbit_ MTF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZNF575, ZNF276, HIC1, ZNF653, ZNF362, ZNF410, PATZ1, PRDM1, HIC2, ZNF76, ZFP91, PRDM6, ZNF296, ZBTB1, SNAI3, SNAI2, ZBTB20, ZNF281, MAZ, ZBTB18, ZNF143, ZBTB16, SNAI1, ZNF148, ZBTB32, ZBTB45, ZBTB7C, ZBTB42, ZNF451, ZNF692, PRDM14, VEZF1, SCRT2, SCRT1, ZNF384, PRDM10 |
| Tissue | NA |
| Tissue Specificity | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. {ECO:0000269|PubMed:8530187}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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