Gene Information
Gene NameSCUBE2
OrganismHomo sapiens (Human)
Gene Length999
Protein NamesSignal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1) (Scube/You)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000175356 )
Evolutionary StageEukaryota
AlphaFoldDBQ9NQ36
Gene CardSCUBE2
Uniprot IDQ9NQ36
PfamPF12662; PF00431; PF12947; PF07645; PF07699
In ASDno
Allosteric Predictionno (-1.095872932)
Ortholog in AnimalsAlpaca_ SCUBE2 ( ortholog_one2one )
Dog_ SCUBE2 ( ortholog_one2one )
GuineaPig_ SCUBE2 ( ortholog_one2one )
Macaque_ SCUBE2 ( ortholog_one2one )
Mouse_ Scube2 ( ortholog_one2one )
Rat_ Scube2 ( ortholog_one2one )
Rabbit_ SCUBE2 ( ortholog_one2one )
OhnologsSCUBE1, SCUBE3
ParalogsSCUBE1, SCUBE3
TissueNA
Tissue SpecificityExpressed in a broad spectrum of adult tissues (PubMed:12270931). {ECO:0000269|PubMed:12270931}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3751055  rs7395988  rs12419343  rs3751057  rs3751059 
Subcellular location [CC]Secreted. Cell surface {ECO:0000269|PubMed:19480626}. Note=Secreted and tethered at the cell surface (PubMed:19480626). {ECO:0000269|PubMed:19480626}.
Mouse PG classificationNA
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