| Gene Information | |
|---|---|
| Gene Name | UBE2T |
| Organism | Homo sapiens (Human) |
| Gene Length | 197 |
| Protein Names | Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T) |
| Target Name | e2 ubiquitin-conjugating enzyme t |
| Target Type | Clinical trial target |
| Gene Age | 1488 ( ENSG00000077152 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NPD8 |
| Gene Card | UBE2T |
| Uniprot ID | Q9NPD8 |
| Pfam | PF00179 |
| In ASD | yes |
| Allosteric Prediction | yes (0.012326521) |
| Ortholog in Animals | Alpaca_ UBE2T ( ortholog_one2one ) Dog_ UBE2T ( ortholog_one2one ) GuineaPig_ UBE2T ( ortholog_one2one ) Macaque_ UBE2T ( ortholog_one2one ) Mouse_ Ube2t ( ortholog_one2one ) Pig_ UBE2T ( ortholog_one2one ) Rat_ Ube2t ( ortholog_one2one ) Rabbit_ UBE2T ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UBE2B, UBE2O, UBE2J2, UBE2A, UBE2C, UBE2H, UBE2V1, UBE2K, UBE2W, UBE2Z, UBE2F, UBE2G2, UBE2I, UBE2V2, UBE2N, UBE2NL, PEDS1, UBE2U, UBE2J1, UBE2G1, UBE2S, CDC34, UBE2R2, AKTIP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1YH2 (X-ray 2.00A ) 4CCG (X-ray 2.40A ) 5NGZ (X-ray 2.40A ) 5OJJ (X-ray 1.85A ) 6R75 (X-ray 2.00A ) 7KZR (EM 4.20A ) 7KZS (EM 4.20A ) 7KZT (EM 4.20A ) 7KZV (EM 4.20A ) |
| DBSNP | rs774357609 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19887602}. Note=Accumulates to chromatin. |
| Mouse PG classification | NA |
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