| Gene Information | |
|---|---|
| Gene Name | NUDT6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 316 |
| Protein Names | Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000170917 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P53370 |
| Gene Card | NUDT6 |
| Uniprot ID | P53370 |
| Pfam | PF00293; PF18290 |
| In ASD | no |
| Allosteric Prediction | yes (0.20894522) |
| Ortholog in Animals | Alpaca_ NUDT6 ( ortholog_one2one ) Dog_ NUDT6 ( ortholog_one2many ) Macaque_ NUDT6 ( ortholog_one2one ) Mouse_ Nudt6 ( ortholog_one2one ) Pig_ NUDT6 ( ortholog_one2one ) Rat_ Nudt6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in liver, kidney and esophagus (at protein level). Ubiquitous. {ECO:0000269|PubMed:11266510, ECO:0000269|PubMed:17569023}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3FXT (X-ray 2.30A ) 3H95 (X-ray 1.70A ) |
| DBSNP | rs12648093 rs1048201 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms. |
| Mouse PG classification | NA |
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